BIOPROCESS DOCUMENT PD-01, Version 2 / 2017-10-20 1. Introduction The FAMI-QS Process Documents are auditable documents established for each process described in Chapter 2 of the FAMI-QS Code of Practice. Such documents include the requirements for the evaluation of the feed safety. Document and take photos of the parts and packaging. Inform the transport company at the time of delivery. Cherokee i love you me rar. Make sure that the transport company documents the incident. Inform local distributors or BPC of the incident. BOX CONTENT When the agitation systems are delivered as part of an instrument from Bioprocess Control. CHEN 451 Process Control 3 cr. CHEN 470 Chemical Process Design 3 cr. CHEN 480 Safety and Loss Prevention 3 cr. CHEN 500 Approved Experience 0 cr. https://greatmotors787.weebly.com/blog/mastering-quickbooks-premier-2005-contractor-edition. Xenserver 6 2 download. CHEN 501 Final Year Project I 3 cr. CHEN 502 Final Year Project II 3 cr. CHEN 541 Biochemical and Bioprocess Engineering 3 cr. 052:185 Process Dynamics and Control in Design Fall 2012 TEXT: Chemical and Bio-Process Control, Third edition James B. Nazmul Karim 2006 Ferret Publishing, Lubbock Texas Supporting Texts: Process Dynamics and Control (2nd ed) Seborg, Edgar, and Mellichamp, Wiley 2004 Introduction to Matlab for Engineers and Scientists. Douglas Etter.
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Chemical And Bioprocess Control Pdf Documents
Chemical And Bioprocess Control Riggs Solution Manual
<ul><li><p>Bioprocess CatalogueProducts and Solutions for the BiopharmaceuticalIndustry</p></li><li><p>3Table of Contents</p><p>About Sartorius 5</p><p>About This Catalogue 6</p><p>Bioprocess Product Finder 8</p><p>Bioprocessing Competence 11Creating Value by Integrated Biomanufacturing 12Fermentors|Bioreactors 15Cell Removal|Clarification 17Capturing|Purification 19Polishing 21Disposable Technologies 23Filter Management|Integrity Testing 25FACTS Program Added Value for Your Business 27Microbiological Quality Control 29Industrial Process Weighing 31</p><p>Fermentation|Cell Culture 33Bioprocess Automation 34Biostat A plus 36Biostat B plus 38Photobioreactor Biostat PBR 50</p><p>Air Filter 55Sartofluor GA 56Aerosart 58Midisart 2000 60Sartosteel 62</p><p>Pre-|Depth Filter 65Jumbo Star 66Sartopure GA 68Sartopure PP2 70Sartopure GF Plus 72Sartopure GF2 74Sartoclean GF 76Sartoclean CA 78Sartofine PP 80</p><p>Sterile Liquid Filters 83Sartobran P 84Sartopore 2 96Sartolon 112Sartofluor LG MaxiCaps 114</p><p>Clarification Filters 117Depth Filter Capsules Sartoclear P 118Depth Filter Capsules Sartoclear P MaxiCaps 120Sartoclear P Depth Filter Modules 122Sartoclear P Depth Filter Sheets 124</p><p>Crossflow Consumables 127Polyethersulfone Mirofiltration Cassettes 128Hydrosart Microfiltration Cassettes 130Polypropylene Microfiltration Cassettes 132Sartocon Single-Use Cassettes 134Polyethersulfone Ultrafiltration Cassettes 136Sartocube Hydrosart Ultrafilter Cassette 138Hydrosart Ultrafiltration Cassettes 140Cellulose Triacetate Ultrafiltration Cassettes 142New Albumin Ultrafiltration Cassettes PESU-MAX 144</p><p>Crossflow Holders & Systems 147Sartocon 2Plus Stainless Steel Holder 148Sartoflow 10 Stainless Steel Holder 150Sartoflow 20 Stainless Steel Holder 152Sartoflow Alpha DL Crossflow System 154Sartoflow Beta Crossflow System 156</p><p>Membrane Chromatography 157Sartobind re-usable 160Sartobind SingleSep 162</p><p>Virus Filter 165Virosart CPV Capsules 166</p><p>Disposable Liquid Handling Systems 171Biopharmaceutical Fluid Handling 172Gammasart BioSystem SA 174Gammasart BioSystem DF 176Sterile Fluid Handling Bags 178Tank Liners & Cylindrical Tanks 182PolyTote Container System 183LevTech Disposable Mixing System 184Fluid Mixing and Control 186Connectors & Accessories 188Disposable Liquid Handling LevTech 192</p><p>Filter Cartridge Housings 201Multi-Rounds Filter Housings 202Single-Rounds Filter Housings 204Sartorius Modular System 206</p><p>Filter Integrity Testing Systems 209Sartocheck Junior BP-Plus 210Sartocheck 3 212Sartocheck 3 EPS 214Sartocheck 4 216Sartocheck 4 MultiUnit 218Sartorius Trolley System 220</p><p>FACTS Services 223DISCOVER 224INCREASE 225CONFIDENCE 226EXPAND 228Biopharm Alliance 229</p><p>Microbiological Control 231Air MonitoringMD8 airscan 232AirPort MD8 233Gelatine Membranes 234Accessories 236Colony CountGridded Membranes 238Microsart e.motion 240Gridded Membranes 242Membranes without Grid 246Hydrophobic Edged Membranes 248Nutrient Pad Sets 250Culture Media and Absorbent Pads 254Biosart 100 Monitors & Media 256Biosart 250 Funnels 259Combisart Systems 260Traditional Filter Holders 264Accessories 268Sterility TestingSterisart NF 274Re-usable System 276</p><p>Weigh|Detect|Control 279Complete Scales 280Process Transmitters|Analogue-Digital Converters 282Indicators 283Load Cells 285System Controllers 287Platforms 288Explosion-protected Weighing Products 290Dynamic Weighing Products 292Average Weight Control|Quality Assurance 293Metal Detectors 295Software Solutions 296</p><p>Chemical Compatibility 298</p><p>Index 304</p><p>Bio-</p><p>proc</p><p>essi</p><p>ng </p><p>Com</p><p>pete</p><p>nce</p><p>Bio-</p><p>proc</p><p>essi</p><p>ng </p><p>Com</p><p>pete</p><p>nce</p><p>Ferm</p><p>en-</p><p>tati</p><p>on|</p><p>Cell </p><p>Cult</p><p>ure</p><p>Air </p><p>Filt</p><p>erPr</p><p>e-|D</p><p>epth</p><p>Filt</p><p>erSt</p><p>erile</p><p> Li</p><p>quid</p><p> Fi</p><p>lter</p><p>s</p><p>Clar</p><p>ific</p><p>a-ti</p><p>on F</p><p>ilter</p><p>sCr</p><p>ossf</p><p>low</p><p>Cons</p><p>um-</p><p>able</p><p>s</p><p>Cros</p><p>sflo</p><p>wSy</p><p>stem</p><p>sM</p><p>embr</p><p>ane</p><p>Chro</p><p>ma-</p><p>togr</p><p>aphy</p><p>Viru</p><p>s Fi</p><p>lter</p><p>Disp</p><p>osab</p><p>leLi</p><p>quid</p><p> Han</p><p>d-lin</p><p>g Sy</p><p>stem</p><p>s</p><p>Filt</p><p>er </p><p>Cart</p><p>ridg</p><p>eH</p><p>ousi</p><p>ngs</p><p>Filt</p><p>er In</p><p>te-</p><p>grit</p><p>y Te</p><p>stin</p><p>gSy</p><p>stem</p><p>s</p><p>FACT</p><p>SM</p><p>icro</p><p>-bi</p><p>olog</p><p>ical</p><p> Co</p><p>ntro</p><p>l</p><p>Wei</p><p>ghDe</p><p>tect</p><p> Co</p><p>ntro</p><p>l</p></li><li><p>4</p></li><li><p>5About Sartorius</p><p>Sartorius is an internationally leading processtechnology supplier covering the segments of biotechnology and mechatronics. TheGoettingen-based company founded in 1870currently employs a good 3,660 persons. Itsbiotechnology segment focuses on filtrationand separation applications, fermenters andproteomics. The mechatronics segment par-ticularly consists of products for weighing,measurement and automation technology inlaboratory and industrial applications.</p><p>Sartorius key customers are from the pharmaceutical, chemical and food and beverage industries and from numerousresearch and educational institutes of the public sector. </p><p>Sartorius has its own production facilities in Europe, Asia and America, as well as salessubsidiaries and local commercial agencies in more than 110 countries.</p></li><li><p>7About this Catalogue</p><p>This process catalogue offers you severaloptions for selecting the optimal product foryour application or process. </p><p>In the first chapter, you will find our offer ofproduct solutions for individual applicationareas all along the process chain, and the corresponding references to the productpages. The thumbnail tabs will help guide you to the section you need to find. </p><p>Alternatively, you can use our BioprocessProduct Finder on page 8. It will assist you in choosing the recommended products for your application. </p><p>The following subjects that cover more thanone application are listed below:Housings, page 201Integrity Testing, page 209Microbiological Testing, page 231Services, page 223</p><p>If you know the name of the product of yourchoice, just check the name index at the backof the catalogue to find the page numberright away.</p></li><li><p>Cell Culture & Fermentation</p><p>Holding Tank</p><p>Fluid Handling Bags | 178</p><p>Fluid Mixing Systems | 186</p><p>Sartofluor GA* | 56</p><p>Sartopure GA* | 68</p><p>Level Control | 286</p><p>Load Cells | 285</p><p>Indicators | 283</p><p>Prefiltration</p><p>Sartopore 20.45 m* | 106</p><p>Sartobran P0.45 m* | 92</p><p>Sartopure GF Plus* | 72</p><p>Sartopure PP2* | 70</p><p>Sartoclean CA* | 78</p><p>Sartoclean GF* | 76</p><p>Prefiltration</p><p>Sartopore 20.45 m* | 106</p><p>Sartobran P0.45 m* | 92</p><p>Sartopure PP2* | 70</p><p>Sartoclean CA* | 78</p><p>Sterile Filtration</p><p>Sartopore 20.2 m* | 96</p><p>Sartobran P0.2 m* | 84</p><p>Filling</p><p>Combics | 281</p><p>Scales | 280</p><p>Platforms | 288</p><p>Load Cells | 285</p><p>Indicators | 283</p><p>Controlling</p><p>Checkweighers | 292</p><p>Scales | 280</p><p>Platforms | 288</p><p>Indicators | 283</p><p>Sterile Filtration</p><p>Sartopore 20.2 m* | 96</p><p>Sartobran P0.2 m* | 84</p><p>Sterile Filtration</p><p>Sartopore 20.2 m* | 96</p><p>Sartobran P0.2 m* | 84</p><p>Fermentation</p><p>Engineering | 229</p><p>Fermenter | 33</p><p>Sartofluor GA* | 56</p><p>Level Control | 286</p><p>Load Cells | 285</p><p>Indicators | 283</p><p>Scales | 280</p><p>Platforms | 288</p><p>Holding Tank</p><p>Fluid Handling Bags | 178</p><p>Fluid Mixing Systems | 186</p><p>Sartofluor GA* | 56</p><p>Level Control | 286</p><p>Load Cells | 285</p><p>Indicators | 283</p><p>Concentration& Diafiltration</p><p>CrossflowUltrafilters* | 136</p><p>CrossflowSystems | 147</p><p>Holding Tank</p><p>Fluid Handling Bags | 178</p><p>Fluid Mixing Systems | 186</p><p>Sartofluor GA* | 56</p><p>Level Control | 286</p><p>Load Cells | 285</p><p>Indicators | 283</p><p>Bioprocess Product Finder</p><p>8</p><p>*Also in disposable technology available.</p><p>Media|Buffer Preparation</p><p>Form & Fill</p></li><li><p>Cell Harvest</p><p>Sartoclear P* | 118</p><p>Crossflow Microfilters* | 128</p><p>CrossflowSystems | 147</p><p>Sartopure GF Plus* | 72</p><p>Sartofine* | 80</p><p>Clarification</p><p>Sartoclear P* | 118</p><p>Crossflow Microfilters* | 128</p><p>CrossflowSystems | 147</p><p>Sartopure GF Plus* | 72</p><p>Sartofine* | 80</p><p>Sartoclean* GF | 76</p><p>Sterile Filtration</p><p>Sartopore 20.2 m* | 96</p><p>Sartobran P0.2 m* | 84</p><p>Membrane ChromatographyPolishing</p><p>SartobindSingleSep* | 162</p><p>Virus Filtration</p><p>Virosart CPV | 166</p><p>Membrane Filtration</p><p>Sartopore 20.1 m* | 104</p><p>Sartobran 0.1 m* | 90</p><p>Holding Tank</p><p>Fluid Handling Bags | 178</p><p>Fluid Mixing Systems | 186</p><p>Sartofluor GA* | 56</p><p>Level Control | 286</p><p>Load Cells | 285</p><p>Indicators | 283</p><p>Concentration & Diafiltration</p><p>CrossflowUltrafilters* | 136</p><p>CrossflowSystems | 147</p><p>Membrane ChromatographyCapturing & Purification</p><p>Sartobindre-usable | 160</p><p>Membrane Filtration</p><p>Sartopore 20.2 m* | 96</p><p>Sartobran P0.2 m* | 84</p><p>9</p><p>Bio-</p><p>proc</p><p>essi</p><p>ng </p><p>Com</p><p>pete</p><p>nce</p><p>Bio-</p><p>proc</p><p>essi</p><p>ng </p><p>Com</p><p>pete</p><p>nce</p><p>Ferm</p><p>en-</p><p>tati</p><p>on|</p><p>Cell </p><p>Cult</p><p>ure</p><p>Air </p><p>Filt</p><p>erPr</p><p>e-|D</p><p>epth</p><p>Filt</p><p>erSt</p><p>erile</p><p> Li</p><p>quid</p><p> Fi</p><p>lter</p><p>s</p><p>Clar</p><p>ific</p><p>a-ti</p><p>on F</p><p>ilter</p><p>sCr</p><p>ossf</p><p>low</p><p>Cons</p><p>um-</p><p>able</p><p>s</p><p>Cros</p><p>sflo</p><p>wSy</p><p>stem</p><p>sM</p><p>embr</p><p>ane</p><p>Chro</p><p>ma-</p><p>togr</p><p>aphy</p><p>Viru</p><p>s Fi</p><p>lter</p><p>Disp</p><p>osab</p><p>leLi</p><p>quid</p><p> Han</p><p>d-lin</p><p>g Sy</p><p>stem</p><p>s</p><p>Filt</p><p>er </p><p>Cart</p><p>ridg</p><p>eH</p><p>ousi</p><p>ngs</p><p>Filt</p><p>er In</p><p>te-</p><p>grit</p><p>y Te</p><p>stin</p><p>gSy</p><p>stem</p><p>s</p><p>FACT</p><p>SM</p><p>icro</p><p>-bi</p><p>olog</p><p>ical</p><p> Co</p><p>ntro</p><p>l</p><p>Wei</p><p>ghDe</p><p>tect</p><p> Co</p><p>ntro</p><p>l</p><p>Capturing IntermediatePurification</p><p>IntermediatePurification</p><p>Polishing</p></li><li><p>Bio-</p><p>proc</p><p>essi</p><p>ng </p><p>Com</p><p>pete</p><p>nce</p></li><li><p>11</p><p>BioprocessingCompetence</p><p>Bio-</p><p>proc</p><p>essi</p><p>ng </p><p>Com</p><p>pete</p><p>nce</p><p>Creating Value by Integrated Biomanufacturing 12</p><p>Fermentors|Bioreactors 15</p><p>Cell Removal|Clarification 17</p><p>Capturing|Purification 19</p><p>Polishing 21</p><p>Disposable Technologies 23</p><p>Filter Management|Integrity Testing 25</p><p>FACTS Program Added Value for Your Business 27</p><p>Microbiological Quality Control 29</p><p>Industrial Process Weighing 31</p></li><li><p>Creating Value by Integrated Biomanufacturing</p><p>12</p><p>Bio-</p><p>proc</p><p>essi</p><p>ng </p><p>Com</p><p>pete</p><p>nce</p><p>Crea</p><p>ting</p><p> Val</p><p>ue b</p><p>y In</p><p>tegr</p><p>ated</p><p> Bio</p><p>man</p><p>ufac</p><p>turin</p><p>g</p><p>Sartorius offers the most com-prehensive technology, productand service portfolio worldwide,which ranges from the discoveryof active ingredients to produc-tion all the way to compliancewith the accompanying regula-tory steps. Featuring special fil-ters, fermenters and bioreactors,products for membrane chroma-tography, bags, containers andmixing systems for fluid mediahandling as well as an extensiveservice portfolio, Sartorius servesall production steps in the bio-pharmaceutical industry. </p><p>Technology from Sartorius makesproduction processes more reli-able, accurate and predictable.Sartorius offers not only productsfor individual production steps,but also technologically and economically optimized solutionsdeveloped together with the customer for complete upstreamand downstream processing. </p><p>Sartorius thinks in processes andtherefore focuses on the factorsthat are critical to success:</p><p> Time to Market Regulatory Compliance Production Costs Production Capacities</p><p>As a result, Sartorius offers itscustomers the unique benefits of a total solution provider.</p><p>Scale-UpSartorius technologies are scal-able so that the customer cangenerate increasing quantities of a substance within a short time throughout all phases, fromdiscovery up to commercial pro-duction and with optimal yield.</p><p>Disposable TechnologyDisposable technology is decisivefor the speed and efficiency ofprocesses, while ensuring maxi-mum security and reliability inpreventing cross-contamination.For all process steps and volumes,Sartorius offers the advantages of powerful and cost-efficientdisposable technology. </p><p>Regulatory ServicesAlong with the BioPharmAlliance jointly founded with KMI|Parexel,Sartorius customers have accessto the entire wealth of expertiseof the market leader in validationand regulatory compliance. </p><p>Validation and TrainingSartorius wont go when thegoing gets tough. Sartorius experienced and highly knowl-edgeable experts help customerswith process validation and training.</p><p>Time to </p><p>Regulary </p><p>Product</p><p>Production </p></li><li><p>13</p><p>Bio-</p><p>proc</p><p>essi</p><p>ng </p><p>Com</p><p>pete</p><p>nce</p><p>Crea</p><p>ting</p><p> Val</p><p>ue b</p><p>y In</p><p>tegr</p><p>ated</p><p> Bio</p><p>man</p><p>ufac</p><p>turin</p><p>g</p><p>Weigh|Detect|ControlSartorius offers a truly wide product and service portfolio forhopper weighing, fill-by-weightlevel control, average weight con-trol of prepackages, completenesschecks and quality assurance. </p><p>EngineeringSartorius engineering expertisecovers customized design, pro-duction, installation, automation,integration and validation ofbioreactors, fermenters andperipheral systems. </p><p>Cell Culture|FermentationTogether with Sartorius BBI Systems, Sartorius offers theproduct and service portfolio of the market leader in cell culture and fermentation, and is focusing on the optimal inter-action between fermentation|cell cultures and downstream processing.</p><p>Process OptimizationTogether with our customers, weanalyze processes and optimizethem in terms of increasing yieldas well as saving time and costs.As a result, Sartorius creates genuine added value for its cus-tomers.</p><p> Market</p><p> Compliance</p><p>ion Costs</p><p> Capacities</p></li><li><p>Bio-</p><p>proc</p><p>essi</p><p>ng </p><p>Com</p><p>pete</p><p>nce</p></li><li><p>15</p><p>Fermentors|BioreactorsIntegrated Solutions from Research Through Production</p><p>Sartorius BBI Systems GmbH has for morethan 35 years provided a range of innovativebioreactor products (BIOSTAT) and supportservices to major biotechnology and pharma-ceutical companies worldwide. In this posi-tion, Sartorius BBI Systems is the worldwideleading supplier of biotechnology systems. </p><p>The BIOSTATline of fermentation and bioreactor equipment spans the full operational spectrum from benchtop andpilot systems to custom process skids.</p><p>The core areas of expertise of Sartorius BBISystems are in the development and production of fermenters and bioreactors for applications in the laboratory, in production and in the corresponding automation and controlling units.</p><p>As part of the Biotechnology Division of Sartorius AG the product portfolio now alsoincludes crossflow filtration equipment inupstream and downstream processing.</p><p>Our capabilitiesOperating internationally, we are always close to our customers around the world. Ourclosely meshed network of agencies, eachwith its own service team, enables us to provide direct, individualized support to ourclients, from the planning stage to operation.This concept to completion approach keepsour clients at the forefront of scientific andtechnical developments.</p><p>Our engineers all over the world tailor systems and whole plants, realizing specificsolutions across the spectrum of customerapplications. Units developed and tested in the laboratory are scaled up to industrialsize in an elaborate and painstaking process.With the aid of special 3D CAD planning procedures, we can show the client their plant at each stage of development.</p><p>With a workforce of a good 500 persons, the company is represented with its pro-duction sites in Germany, Italy, the U.S, andIndia, and with sales companies in more than 50 countries.</p><p>Practical solutions at every levelOur portfolio of capabilities spans all areas of customer support. From technical con-sultation to project planning, in areas such aslaboratory automation, industrial poduction,validation support and after sales service, we handle it all.</p><p>Sartorius BBI Systems is a valuable partner for companies in the pharmaceutical andbiotech market where cGMP requirements and FDA guidelines must be followed.Equipment and plants supplied by SartoriusBBI Systems are fully documented as built. </p><p>Discover our capabilities on page 33. </p><p>Bio-</p><p>proc</p><p>essi</p><p>ng </p><p>Com</p><p>pete</p><p>nce</p><p>Ferm</p><p>ento</p><p>rs|B</p><p>iore</p><p>acto</p><p>rs</p></li><li><p>Bio-</p><p>proc</p><p>essi</p><p>ng </p><p>Com</p><p>pete</p><p>nce</p></li><li><p>17</p><p>Cell Removal|Clarification</p><p>Within the biotech industry, cell culture and microbial fermentation are todays keyprocesses for the production of therapeuticproteins. Key technologies relevant in theupstream and downstream processing of cellculture and microbial fermentation mainlyinvolve filtration and purification. </p><p>Purification steps such as chromatographyare very cost-intensive. Chromatography performance depends significantly on theprior removal of particulate matter, especiallycell and cell..</p></li></ul>